Title: Faculty & research interests

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Rene Hen, PhD
Professor
Full Member

Department: Neuroscience
Psychiatry
Pharmacology


212-543-5328
rh95@columbia.edu


Personal Website

Disease Models:

Stem Cell Categories:

Model Organisms: Mouse

Themes: Brain



Professor Hen's research is aimed at understanding the mechanism of action of medications that are currently used to treat depression and anxiety-related disorders. Although selective serotonin re-uptake inhibitors (SSRI) are the most commonly prescribed antidepressants and anxiolytics, their mechanisms of action, and particularly the reason for their delayed (4-6 weeks) onset of therapeutic efficacy, are largely unknown. The general hypothesis his team is studying is that the generation of new neurons from a pool of undifferentiated stem cells located in a part of the brain called the hippocampus, contributes to the delayed onset of action of SSRIs.

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