Title: Faculty & research interests

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Neil  Shneider
Neil Shneider, MD, PhD
Assistant Professor
Associate Member

Department: Neurology

P&S 5-423
212-342-3107
ns327@columbia.edu


Personal Website

Disease Models: Neurodegenerative Diseases, Neurological Diseases

Stem Cell Categories: ES and other embryonic stem cells, iPS cells

Model Organisms: Human, Rodent

Themes: Brain, Neurodegeneration

Neil Shneider is a physician-scientist interested in neuromuscular development and disease. He is a graduate of Harvard College and of the MD-PhD program of the Columbia University College of Physicians and Surgeons. Dr. Shneider has clinical expertise in the diagnosis and care of patients with ALS and related motor neuron diseases and is an attending physician in the Eleanor and Lou Gehrig MDA/ALS Multidisciplinary Care Center. He is a member of the Center for Motor Neuron Biology and Disease and of the H. Houston Merritt Clinical Research Center. His research efforts focus on the molecular development of sensorimotor neural circuits and mechanisms of motor neuron degeneration in amyotrophic lateral sclerosis.



Publications:

Shneider, N.A., Brown, M.N., Smith, C.A., Pickel, J., Alvarez, F.J.
Gamma motor neurons express distinct genetic markers at birth and require muscle spindle-derived GDNF for postnatal survival. Neural Development 4(42):. (2009)

Shneider, N.A., Mentis, G.Z., Schustak, J., O’Donovan, M.J.
Functionally reduced sensorimotor connections form with normal specificity despite abnormal muscle spindle development: the role of spindle-derived neurotrophin 3. Journal of Neuroscience 29(15):4719-35. (2009)

Hippenmeyer S, Shneider N.A., Birchmeier C, Burden S.J., Jessell T.M., and Arber S
A Role for Neuregulin-1 Signaling in Muscle Spindle Differentiation. Neuron 36(6):1035-1049. (2002)

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