Title: Faculty & research interests

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Donald W Landry
Donald W Landry, MD, PhD
Samuel Bard Professor and Chairman of Medicine
Physician-in Chief, NYP/Columbia

Associate Member

Department: Medicine-Nephrology

PH, 8th floor, Rm 105
212-305-5838
dwl1@columbia.edu


Personal Website

Disease Models: Drug Screening

Stem Cell Categories: ES and other embryonic stem cells

Model Organisms: Human, Rodent

Themes: Stem Cell Biology

Donald W. Landry, M.D., Ph.D., is Samuel Bard Professor of Medicine, Director of the Division of Experimental Therapeutics, and the Chair of the Department of Medicine. His basic research program focuses on drug discovery and artificial enzyme approaches to intractable drug targets, e.g., cocaine addiction. His discovery of vasopressin deficiency and hypersensitivity in vasodilatory shock is the focus of his clinical research. He has pioneered the harvesting of live blastomeres from dead embryos as a source of human embryonic stem cells.



Publications:

Bao G, Clifton M, Hoette T, Mori K, Deng S, Qiu A, Viltard M, Williams D, Paragas, N, Leete T, Kulkarni R, Li X, Lee B, Kalandadze A, Ratner AJ, Pizarro JC, Schmidt-Ott K, Landry DW, Raymond K, Strong RK, Barasch J.
Iron traffics in circulation bound to a siderocalin (Ngal)–catechol complex. Nature Chemical Biology in press:. (2011)

Nguyena TH, Peib R, Landry DW, Stojanovic MN, Lina Q.
Microfluidic aptameric affinity sensing of vasopressin for clinical diagnosis and therapeutic applications. Sensor Actuat B-Chem. in press:. (2011)

Gavrilov S, Prosser R, Khalid I, Macdonald J, Sauer MV, Landry DW, & Papioannou VE.
Non-viable human embryos as a source of viable cells for embryonic stem cell derivation. Reprod BioMed Online 18:301-8. (2009)

Gong G, Xie Y, Liu Y, Rinderspacher A, Deng SX, Feng Y, Zhu Z, Tang Y, Wyler M, Aulner N, Toebben U, Smith DH, Branden L, Chung C, Schürer S, Vidović D, Landry DW.
Discovery of novel small molecule cell type-specific enhancers of NF-kappaB nuclear translocation. Bioorg Med Chem Lett. 19(4):1191-4. (2009)

Gao D, Narashihan DL, Macdonald J, Brim R, Ko M-C, Landry DW, Woods JH, Sunahara R, Zhan C-G.
Thermostable variants of cocaine esterase for long-time protection against cocaine toxicity. Mol Pharmacol 5:. (2008)

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